We believe the purity and performance of the product matter. That’s why we take the time to double filter our smart toxin with a proprietary XTRACT Technology™ process.
The unique formula removes unnecessary proteins so the active ingredient contains only what is needed to smooth frown lines, treatment after treatment. Time is on your side, and so are we.
Frown lines form when facial expressions are made as the muscle under the skin contracts. Over time, as your skin ages, these repeated expressions cause lasting frown lines. Neurotoxins, such as Xeomin®, are prescription medications that block the release of chemicals that cause these muscle contractions so frown lines are softened.
Xeomin® is made through a unique precision manufacturing process called XTRACT Technology™, that uses two filtration steps to isolate the therapeutic component of the molecule and removes the complexing/unnecessary proteins that don’t play an active role in treatment. Xeomin® is a double filtered neurotoxin. Head-to-head studies evaluating the relative risk of immunogenicity due to the presence or absence of complexing/unnecessary proteins have not been performed.
Xeomin® (incobotulinumtoxinA) is a prescription medication injected into muscles and used to temporarily improve the appearance of moderate to severe frown lines between the eyebrows (glabellar lines) in adults. Xeomin® contains botulinum toxin type A, a protein purified from the bacterium Clostridium botulinum.
When you squint or frown, the muscles between your eyebrows contract, causing the skin to furrow and fold. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent frown lines. Botulinum toxin type A – the active ingredient in Xeomin®– acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, Xeomin® can temporarily reduce the lines between your eyebrows.
Xeomin® was proven effective in two randomized, double-blind, multicenter, placebo-controlled clinical trials of 547 healthy, adult patients. The average age of patients in the study was 46 years. Patients received 20 Units of Xeomin® and were classified as responders if they had a 2-grade improvement on a 4-point scale as assessed by the physician and patient. Using these criteria, treatment success was higher with Xeomin® than placebo on Day 30 in both studies (60% and 48% vs. 0% for placebo in both studies). Based on these trials, Xeomin® received FDA approval for use in glabellar lines in 2011.
During treatment, which usually takes about 10-20 minutes, Dr. Samuels or an associate will inject Xeomin® into the muscles in your forehead that cause frown lines between your eyebrows. No anesthesia is required; however, we may use a topical anesthetic or cold pack to reduce any discomfort.
If you are an adult with moderate to severe glabellar lines, Xeomin® may be right for you. Talk to Dr. Samuels to discuss the benefits and risks of treatment. Do not use Xeomin® if you are allergic to botulinum toxin or any of the other ingredients in Xeomin®. You should also not use Xeomin® if you have had an allergic reaction to any other botulinum toxin product or have a skin infection at the planned injection site.
You may begin to see visible smoothing as early as 3-4 days after injection. The median first onset of effect was less than a week. The maximum effect occurred at 30 days. The typical duration of effect was up to 3 months in clinical trials but may last significantly longer or shorter in individual patients.
Xeomin® may cause serious side effects, including allergic reactions. Symptoms of an allergic reaction to Xeomin® may include: itching, rash, redness, swelling, wheezing, asthma symptoms, or dizziness or feeling faint. Contact Dr. Samuel’s office or seek medical help right away if you have wheezing, experience other asthma symptoms, or if you become dizzy or faint.In clinical trials of Xeomin® for the treatment of frown lines between the eyebrows, headache was the most common side effect. Xeomin® may cause loss of strength or general muscle weakness, blurred vision, or drooping eyelids within hours to weeks of taking Xeomin®. If this happens, do not drive a car, operate machinery, or do other dangerous activities. Tell Dr. Samuels if you have any side effect that bothers you or that does not subside. These are not all of the possible side effects of Xeomin®. Please ask Dr. Samuels for more information.
For more information about Xeomin or to see if you’re a good candidate for this procedure, schedule a consultation with Dr. Samuels at 502-897-9411.
Our practice serves Louisville, KY and the surrounding areas.
