The O-Shot® is a nonsurgical procedure that uses a woman’s own platelet-rich plasma (PRP) from a simple blood draw to rejuvenate vaginal tissues and enhance sexual pleasure. The FDA-approved treatment activates the body’s stem cells to rejuvenate and revitalize vaginal and clitoral function, helping women experience orgasms with increased intensity. Dr. Samuels is one of the few physicians in Kentucky trained and endorsed by the Cellular Medicine Association to perform this breakthrough procedure.


The in-office procedure starts with a simple blood draw from your arm. Then, platelets and growth factors are separated to create PRP. After applying a numbing cream and injection block to the clitoris and vaginal area, a very thin needle is used to inject the PRP to the clitoral hood and into the roof of the vagina directly under the female urethra, which is the most important area for female sexual pleasure (called the O-Space).  The process takes about 20 minutes, and women experience little to no discomfort. You experience the benefit of the O-Shot almost immediately, with full rejuvenation benefits after about 3 months.

O-Shot® treatment results:

  • Improvement or resolution of lichen sclerosus
  • Greater arousal from clitoral stimulation
  • Rejuvenated skin of the vulva
  • Tightening of the vaginal opening
  • Stronger orgasm
  • Increased sexual desire
  • Increased ability to have vaginal orgasms
  • Increased lubrication
  • Decreased pain for those suffering from painful intercourse
  • Decreased stress urinary incontinence

Frequently Asked Questions

The O-Shot is a nonsurgical treatment that aims to increase sexual arousal and rejuvenate the vagina. Patients report greater arounsal, stronger and more frequent orgasms and increased natural lubrication after the procedure.

The shot works by using platelet-rich plasma (PRP) produced from the patient’s own blood. PRP contains cell regenerating growth factors that, when injected into specific areas of the vagina, trigger stem cells to increase blood flow and generate healthy tissue growth while improving vascularization of the area.

Getting the O-Shot is nearly painless.  We numb the area with a gentle, cream-based product so that the ensuing clitoral block injection is nearly painless as well. Although every patient’s experience is different, most experience only minor discomfort. The injection feels like a slight pinch or warm sensation. There is no recovery time with this nonsurgical procedure. It generally takes about 30 minutes to complete, including the numbing process. 

PRP Procedure

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Talk about your options during a private consultation

Almost 50% of women have some type of sexual disorder, and most are uncomfortable talking about it. Dr. Samuels and her staff will make you feel completely at ease as soon as you enter the office. During the initial consultation, Dr. Samuels listens to your concerns and questions and recommends the best solution for you.

For more information about O-Shot or to see if you’re a good candidate for this procedure, schedule a consultation with Dr. Samuels at 502-897-9411.

Our practice serves Louisville, KY and the surrounding areas.